Screening for Right-to-Left Shunts With Contrast Transcranial Doppler in Hereditary Hemorrhagic Telangiectasia

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Screening for right-to-left shunts with contrast transcranial Doppler in hereditary hemorrhagic telangiectasia.

BACKGROUND AND PURPOSE Contrast transthoracic echocardiography (TTCE) is used to screen hereditary hemorrhagic telangiectasia (HHT) patients for right-to-left shunts (RLS) associated with increased stroke risk. We hypothesized that contrast transcranial Doppler (TCDc), shown to be highly sensitive for detecting RLS in patent foramen ovale, will be as comparable to TTCE for screening HHT patient...

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Optimizing the technique of contrast transcranial Doppler ultrasound in the detection of right-to-left shunts.

BACKGROUND AND PURPOSE A cardiac right-to-left shunt (RLS) can be identified by transesophageal echocardiography and transcranial Doppler ultrasound (TCD) with contrast agents and a Valsalva maneuver (VM) as a provocation procedure. This article applies the modalities of these tests detailed in previous studies to a large patient cohort and compares 2 contrast agents (saline and Echovist-300). ...

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Contrast Transcranial Doppler Ultrasound in the Detection of Right-to-Left Shunts

Background and Purpose—Cardiac right-to-left shunts can be identified by transcranial Doppler ultrasound (TCD) with the use of different contrast agents and by transesophageal echocardiography (TEE). Systematic data are available on neither the reproducibility of contrast TCD, the comparison of different contrast agents, nor the comparison of simultaneous bilateral to unilateral recordings. Fur...

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Methodological parameters influence the detection of right-to-left shunts by contrast transcranial Doppler ultrasonography.

BACKGROUND AND PURPOSE Contrast transcranial Doppler ultrasonography is a new method to detect intracardiac right-to-left shunts, such as the patent foramen ovale. However, the methodology of the procedure varies considerably among investigators. This study was undertaken to assess the influence of methodological parameters on the results of the contrast transcranial Doppler examination in the ...

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Contrast transcranial Doppler ultrasound in the detection of right-to-left shunts: comparison of different procedures and different contrast agents.

BACKGROUND AND PURPOSE Cardiac right-to-left shunts can be identified by transesophageal echocardiography (TEE) and by transcranial Doppler ultrasound (TCD) with the use of different contrast agents and different provocation procedures. Currently, data on an appropriate time window for the appearance of contrast bubbles in the TCD recording after the injection of the contrast medium and the com...

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ژورنال

عنوان ژورنال: Stroke

سال: 2011

ISSN: 0039-2499,1524-4628

DOI: 10.1161/strokeaha.110.608224